国际影响力：
1. 建立多能干细胞来源的间充质干细胞及应用的先驱团队之一；
2. 合成生物使能技术构建调控元器件的工程细胞；
3. 领导亚洲首例造血干细胞基因治疗异染性脑白质退化症，患者长期恢复健康生活；
4. 建立香港大学首个符合国际药品检查组织(PIC/S) GMP标准的细胞治疗制造中心；
5. 2004年 美国华人生物科学家协会（SCBA）青年科学家奖；2007年香港大学健康老龄化国际大会青年科学家奖；2012年国际干细胞研究学会（ISSCR）年会旅行奖；2023年香港大学李嘉诚医院杰出研究奖；2024年深圳理工大学科研贡献奖。
承担项目：
1.2023年-2028年：国家重点研发计划:靶向肿瘤细胞死亡的时空干预技术与合成生物学策略，在研；
2.2022年-2027年：国家科技部重点研发计划:干细胞在新型冠状病毒肺炎发病机制和损伤修复中的作用，在研；
3.2025年-2007年：深圳市科技计划项目：基于多能干细胞与线粒体功能重建的术后肝损伤修复研究，在研。
代表性文章：
迄今已发表研究论文 190余篇，具体论文可通过以下平台查阅：
PubMed（生物医学文献数据库）；Google学术(https://scholar.google.com/citations?user=I1j8ZWcAAAAJ&hl=en)
1. Zhang Z, Jiang H, Huang L, Liu S, Zhou X, Cai Y, Li M, Gao F, Liang X, Tsang KS, Chen G, Ma CY, Chai YH, Liu H, Yang C, Yang M, Zhang X, Han S, Du X, Chen L, Hwu WL, Zhuo J, Lian Q*. Lentivirus-modified hematopoietic stem cell gene therapy for advanced symptomatic juvenile metachromatic leukodystrophy: A long-term follow-up pilot study. Protein Cell, 2025, 16(1): 16- 27; doi: 10.1093/procel/pwae037.
2. Ma CY, Zhai Y, Li CT, Liu J, Xu X, Chen H, Tse HF*, Lian Q*. Translating mesenchymal stem cell and their exosome research into GMP compliant advanced therapy products: Promises, problems and prospects. Medicinal Research Reviews. 2024 May;44(3):919-938
3. Jin L, Geng L, Ying L, Shu L, Ye K, Yang R, Liu Y, Wang Y, Cai Y, Jiang X, Wang Q, Yan X, Liao B, Liu J, Duan F, Sweeney G, Woo CWH, Wang Y, Xia Z, Lian Q*, Xu A*. FGF21-Sirtuin 3 Axis Confers the Protective Effects of Exercise Against Diabetic Cardiomyopathy by Governing Mitochondrial Integrity. Circulation. 2022 Nov 15;146(20):1537-1557.
4. Geng L, Liao B, Jin L, Yu J, Zhao X, Zhao Y, Zhong L, Wang B, Li J, Liu J, Yang JK, Jia W, Lian Q*, Xu A*. β-Klotho promotes glycolysis and glucose-stimulated insulin secretion via GP130. Nature Metabolism. 2022 May;4(5):608-626. doi: 10.1038/s42255-022-00572-2.
5. Lian Q*, Zhang K, Zhang Z, Duan F, Guo L, Luo W, Mok BW, Thakur A, Ke X, Motallebnejad P, Nicolaescu V, Chen J, Ma CY, Zhou X, Han S, Han T, Zhang W, Tan AY, Zhang T, Wang X, Xu D, Xiang J, Xu A, Liao C, Huang FP, Chen YW, Na J, Randall G, Tse HF, Chen Z, Chen Y, Chen HJ*. Differential effects of macrophage subtypes on SARS-CoV-2 infection in a human pluripotent stem cell-derived model. Nature Communications. 2022 Apr 19;13(1):2028. doi:10.1038/s41467-022-29731-5.
6. Zhang Z, Guo L ,Huang L, Zhang C.., Tse HF, Xia H, Lian Q*. Distinct disease severity between children and older adults with COVID-19: Impacts of ACE2 expression, distribution, and lung progenitor cells . Clin Infect Dis. 2021 Jan 3:ciaa1911. doi: 10.1093/cid/ciaa1911
7. Zhang Z, Yan B, Gao F, Li Q, Meng X, Chen P, Zhou L, Deng W, Li C, Xu W, Han S, Feng H, Li Y, Chen J, Yin Z, Liao C, Tse HF*, Xu A*, Lian Q*. Pluripotent Stem Cells Reveal Poly-unsaturated Fatty Acids-provoked Mitochondrial Stress as a Central Node Potentiating Retinal Pigmented Epithelium Degeneration in Bietti’s Crystalline Dystrophy . Molecular Therapy 2020 Jul 25;S1525-0016(20)30375-0
8. Zhang Y, Zhang Z, Chen P, Ma CY, Li C, Au TYK, Tam V, Peng Y, Wu R, Cheung KMC, Sham PC, Tse HF, Chan D, Leung VY, Cheah KSE*, Lian Q*. Directed Differentiation of Notochord-like and Nucleus Pulposus-like Cells Using Human Pluripotent Stem Cells. Cell Reports 2020 Feb 25;30(8):2791-2806.e5
9. Fu QL, Chow YY, Sun SJ ,Zeng QX, Li HB, Shi JB, Sun YQ, Wen W, Tse HF, Lian Q*, Xu G*. Mesenchymal stem cells derived from human induced pluripotent stem cells modulate T-cell phenotypes in allergic rhinitis. Allergy. 2012 Oct;67(10):1215-22.doi: 10.1111/j.1398-9995.2012.02875.x.
10. Lian Q*, Zhang Y, Zhang J, Zhang HK, Wu X, Zhang Y, Lam FF, Kang S, Xia JC, Lai WH, Au KW, Chow YY, Siu CW, Lee CN, Tse HF*. Functional mesenchymal stem cells derived from human induced pluripotent stem cells attenuate limb ischemia in mice. Circulation. 2010 Mar 9;121(9):1113-20
