代表性论文：
1.R Qiu, RS Lewis. Structural rearrangements underlying the activation of STIM1 by ER calcium depletion. Proceedings of the National Academy of Sciences. (accepted)
2.R Qiu, RS Lewis. Multiple weak brakes act in concert to control STIM1 and store-operated calcium entry.Proceedings of the National Academy of Sciences.2025,122(50): e2518622122.
Selected for commentary in PNAS (“Listening to the quiescence of single STIM1 dimers”, P.G. Hogan)
3.R Qiu, RS Lewis. Structural features of STIM and Orai underlying store-operated calcium entry. Current Opinion in Cell Biology. 2019, 57: 90-98.
4.S van Dorp,R Qiu, UB Choi, MM Wu, M Yen, M Kirmiz, A T Brunger, R S Lewis. Conformational dynamics of auto-inhibition in the ER calcium sensor STIM1. eLife. 2021, 10: e66194.
5.J Xu#,R Qiu#, AM Garces, H Hübner, X Xu, C Hao, D Weikert, P Gmeiner, AT Brunger. The role of intrinsically disordered domains in regulating G protein-coupled receptor signaling. Journal of the American Chemical Society. 2026.
6.R Qiu, VC DeRocco, C Harris, A Sharma, MM Hingorani, DA Erie, KR Weninger.Large conformational changes in MutS during DNA scanning, mismatch recognition and repair signalling. The EMBO Journal. 2012, 31(11): 2528-2540.
7.R Qiu, M Sakato, E J Sacho, H Wilkins, X Zhang, P Modrich, MM Hingorani, KR Weninger, DA Erie.MutL traps MutS at a DNA mismatch. Proceedings of the National Academy of Sciences. 2015, 112(35): 10914-10919.
8.Y Cao#, H Chen#,R Qiu, M Hanna, E Ma, M Hjort, A Zhang, RS Lewis, JC Wu, NA Melosh. Universal intracellular biomolecule delivery with precise dosage control. Science Advances. 2018, 4(10): eaat8131.
9.Y Cao#, E Ma#, S Cestellos-Blanco, B Zhang,R Qiu, Y Su, JA Doudna, P Yang. Nontoxic nanopore electroporation for effective intracellular delivery of biological macromolecules. Proceedings of the National Academy of Sciences. 2019, 116(16): 7899-7904.
10.K Rajagopalan#,R Qiu#, S M Mooney, S Rao, T Shiraishi, E Sacho, H Huang, E Shapiro, K R Weninger, P Kulkarni. Cancer/testis antigen PAGE4, a regulator of c-Jun transactivation, is phosphorylated by homeodomain-interacting protein kinase 1, a component of the stress-response pathway. Biochemistry. 2014, 53(10): 1670-1679.
11.SM Mooney,R Qiu, JJ Kim, EJ Sacho, K Rajagopalan, D Johng, T Shiraishi, P Kulkarni, KR Weninger. Cancer/testis antigen PAGE4, a regulator of c-Jun transactivation, is phosphorylated by homeodomain-interacting protein kinase 1, a component of the stress-response pathway. Biochemistry. 2014, 53(10): 1670-1679.
12.B Hellenkamp#, S Schmid#, O Doroshenko, O Opanasyuk, R Kühnemuth, S Rezaei Adariani, B Ambrose, M Aznauryan, A Barth, V Birkedal, ME Bowen, H Chen, T Cordes, T Eilert, C Gebhardt, M Götz, G Gouridis, E Gratton, T Ha, P Hao, CA Hanke, A Hartmann, J Hendrix, LH Hildebrandt, V Hirschfeld, J Hohlbein, B Hua, CG Hübner, E Kallis, AN Kapanidis, J-Y Kim, G Krainer, DC Lamb, NK Lee, EA Lemke, B Levesque, M Levitus, JJ McCann, N Naredi-Rainer, D Nettels, T Ngo,R Qiu, N C Robb, C Röcker, H Sanabria, M Schlierf, T Schröder, B Schuler, H Seidel, L Streit, J Thurn, P Tinnefeld, S Tyagi, N Vandenberk, AM Vera, KR Weninger, B Wünsch, IS Yanez-Orozco, J Michaelis, CAM Seidel, TD Craggs, T Hugel. Precision and accuracy of single-molecule FRET measurements—a multi-laboratory benchmark study. Nature Methods. 2018, 15(9): 669-676.
